Angela Paterna

Research staff

11/2019 - present PostDoc Fellowship at the CNR – IBF Palermo 04/2018 - 09/2019 Research Fellowship at the CNR – ICB Catania 05/2017 PhD in Pharmacy, Speciality in Pharmaceutical and Therapeutic Chemistry (SFRH/BD/77612/2011) at the Research Institute for Medicines (iMed.ULisboa, Lisbon) Faculty of Pharmacy, University of Lisbon (Natural Product Chemistry group). 05/2011-04/2012 Research fellowship (PTDC/QUI-QUI/099815/2008) at the Research Institute for Medicines (iMed.ULisboa, Lisbon) University of Lisbon. 10/2010 Master Degree in Chemistry and Pharmaceutical Technology at the Faculty of Pharmacy, University of Palermo, Italy.

orcid://0000-0002-4903-4143,

Contact:

- Email angela.paterna@ibf.cnr.it
- Phone +39-091-6809556
- Location Palermo

Research interests:

- Cell-based technologies and bioactives for research and innovation (Cell-Tech Hub)

Key publications:

Adamo et al. Journal of Extracellular Vesicles, 2021, 10(6), e12081

Raimundo et al. British Journal of Pharmacology, 2021, 178 (18), pp. 3627 - 3647

Sanfilippo et al. Bioorganic Chemistry, 2019, 93, 103325

Paterna et al. Bioorganic and Medicinal Chemistry, 2018, 26(2), pp. 421–434

Paterna et al. European Journal of Medicinal Chemistry, 2017, 128, pp. 247–257

Publications (9):

DetectEV: A functional enzymatic assay to assess integrity and bioactivity of extracellular vesicles
Adamo, Giorgia; Picciotto, Sabrina; Gargano, Paola; Paterna, Angela; Raccosta, Samuele; Rao, Estella; Romancino, Daniele Paolo; Ghersi, Giulio; Manno, Mauro; Salamone, Monica; Bongiovanni, Antonella
JOURNAL OF EXTRACELLULAR VESICLES, 14, 2025
DOI: 10.1002/jev2.70030

Antioxidant properties and bioactivity of three marine microalgae on human cancer cell lines
Herbert, H.; Parkes, R.; Barone, M. E.; Mcdonnell, A.; Picciotto, S.; Adamo, G.; Paterna, A.; Manno, M.; Bongiovanni, A.; Touzet, N.; Campion, E.
Applied Phycology, 5, 2024
DOI: 10.1080/26388081.2024.2382146

Effects of Cultivation Stress on the Glaucophyte Cyanophora paradoxa and Bioactive Potential in Human Cancer Cell Lines
Herbert, H.; Parkes, R.; Barone, M. E.; Picciotto, S.; Adamo, G.; Paterna, A.; Manno, M.; Bongiovanni, A.; Campion, E.; Touzet, N.
PHYCOLOGIA, 63, 2024
DOI: 10.1080/00318884.2024.2330341

Extracellular vesicles from the microalga Tetraselmis chuii are biocompatible and exhibit unique bone tropism along with antioxidant and anti-inflammatory properties
Adamo, Giorgia; Santonicola, Pamela; Picciotto, Sabrina; Gargano, Paola; Nicosia, Aldo; Longo, Valeria; Aloi, Noemi; Romancino, Daniele; Paterna, Angela; Rao, Estella; Raccosta, Samuele; Noto, Rosina; Salamone, Monica; Deidda, Irene; Costa, Salvatore; DI SANO, Caterina; Zampi, Giuseppina; Morsbach, Svenja; Landfester, Katharina; Colombo, Paolo; Wei, Mingxing; Bergese, Paolo; Touzet, Nicolas; Manno, Mauro; DI SCHIAVI, Elia; Bongiovanni, Antonella
COMMUNICATIONS BIOLOGY, 7, 2024
DOI: 10.1038/s42003-024-06612-9

alphaS1-Casein administration to a C. elegans model of Alzheimer's disease through proteoliposome delivery
Carrotta, Rita; Paterna, Angela; Santonicola, Pamela; DI PRIMA, Giulia; Rao, Estella; Raccosta, Samuele; Zampi, Giuseppina; Oscar, Moran; Manno, Mauro; DI SCHIAVI, Elia; Librizzi, Fabio
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 52, 2023

αS1-Casein-Loaded Proteo-liposomes as Potential Inhibitors in Amyloid Fibrillogenesis: In Vivo Effects on a C. elegans Model of Alzheimer’s Disease
Paterna, A.; Santonicola, P.; Di Prima, G.; Rao, E.; Raccosta, S.; Zampi, G.; Russo, C.; Moran, O.; Manno, M.; Di Schiavi, E.; Librizzi, F.; Carrotta, R.
ACS CHEMICAL NEUROSCIENCE, 14, 2023
DOI: 10.1021/acschemneuro.3c00239

Extracellular Vesicles From Microalgae: Uptake Studies in Human Cells and Caenorhabditis elegans
Picciotto, Sabrina; Santonicola, Pamela; Paterna, Angela; Rao, Estella; Raccosta, Samuele; Romancino Daniele, Paolo; Noto, Rosina; Touzet, Nicolas; Manno, Mauro; DI SCHIAVI, Elia; Bongiovanni, Antonella; Adamo, Giorgia
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 10, 2022
DOI: 10.3389/fbioe.2022.830189

Isolation of extracellular vesicles from microalgae: Towards the production of sustainable and natural nanocarriers of bioactive compounds
Picciotto, Sabrina; Barone, Maria E.; Fierli, David; Aranyos, Anita; Adamo, Giorgia; Bo?i?, Darja; Romancino, Daniele P.; Stanly, Christopher; Parkes, Rachel; Morsbach, Svenja; Raccosta, Samuele; Paganini, Carolina; Cusimano, Antonella; Martorana, Vincenzo; Noto, Rosina; Carrotta, Rita; Librizzi, Fabio; Capasso Palmiero, Umberto; Santonicola, Pamela; Igli?, Ales; Gai, Meiyu; Corcuera, Laura; Kisslinger, Annamaria; Di Schiavi, Elia; Landfester, Katharina; Liguori, Giovanna L.; Kralj-Igli?, Veronika; Arosio, Paolo; Pocsfalvi, Gabriella; Manno, Mauro; Touzet, Nicolas; Bongiovanni, Antonella
biomaterials science (print)issn: 2047-4830royal society of chemistry, 9, 2021
DOI: 10.1039/d0bm01696a

Nanoalgosomes: Introducing extracellular vesicles produced by microalgae
Adamo, Giorgia; Fierli, David; Romancino, Daniele P.; Picciotto, Sabrina; Barone, Maria E.; Aranyos, Anita; Bo?i?, Darja; Morsbach, Svenja; Raccosta, Samuele; Stanly, Christopher; Paganini, Carolina; Gai, Meiyu; Cusimano, Antonella; Martorana, Vincenzo; Noto, Rosina; Carrotta, Rita; Librizzi, Fabio; Randazzo, Loredana; Parkes, Rachel; Capasso Palmiero, Umberto; Rao, Estella; Paterna, Angela; Santonicola, Pamela; Igli?, Ales; Corcuera, Laura; Kisslinger, Annamaria; Di Schiavi, Elia; Liguori, Giovanna L.; Landfester, Katharina; Kralj-Igli?, Veronika; Arosio, Paolo; Pocsfalvi, Gabriella; Touzet, Nicolas; Manno, Mauro; Bongiovanni, Antonella
journal of extracellular vesiclesissn: 2001-3078järfälla : co-action pub., 10, 2021
DOI: 10.1002/jev2.12081