Personal Card



Cristina Potrich

Associate

C.P. is senior researcher at FBK and associate to CNR-IBF. Her main interest are biofunctional surfaces applied to biosensors and Lab-on-a-chip for medical and agri-food applications (4 patents). C.P. graduated with honors in biology and obtained her PhD in Molecular Physiology and Structural Biology from UniPD, Italy. She also obtained the National Scientific Qualification as Associate Professor in Applied Physics (02/D1). Visiting scientist in many European laboratories, she co-organized several congresses (national and international) and international schools. She is referee for many leading journals and author of more than 60 papers published in international journals, book chapters and many contributions to congresses with review.

orcid://0000-0002-0793-7547,

Contact:

- Email cristina.potrich@ibf.cnr.it
- Phone +39-0461-31605
- Location Trento

Research interests:

- Biosurfaces for Lab-on-a-chip and biosensors (Principal investigator)

Key publications:

Potrich C, Chalyan T, Schreuder E, Falke F, Pasquardini L, Pederzolli C, Heideman R, Pavesi L. (2019) AFM1 Detection in Milk by Fab' Functionalized Si3N4 Asymmetric Mach-Zehnder Interferometric Biosensors. Toxins (Basel). 2019 Jul 14;11(7). doi: 10.3390/toxins11070409.

Potrich C, Lunelli L, Cocuzza M, Marasso SL, Pirri CF, Pederzolli C. (2019). Simple PDMS microdevice for biomedical applications. Talanta. 2019 Feb 1;193:44-50. doi: 10.1016/j.talanta.2018.09.080.

L. Pasquardini, A. Roncador, V. Prusakova, L. Vanzetti, C. Potrich, L. Lunelli, C. Pederzolli, S. Iannotta, P. Macchi, S. Dirè (2021) Functionalization of TiO2 sol-gel derived films for cell confinement. Colloids and Surfaces B: Biointerfaces 204 (2021) 111787

Rocco Carcione, Sara Politi, Erica Iacob, Cristina Potrich, Lorenzo Lunelli, Lia Emauela Vanzetti, Ruben Bartali, Victor Micheli, Giancarlo Pepponi, Maria Letizia Terranova, Emanuela Tamburri (2020) Exploring a new approach for regenerative medicine: Ti-doped polycrystalline diamond layers as bioactive platforms for osteoblast-like cells growth. Applied Surface Science 540 (2021) 148334

Notarangelo M, Zucal C, Modelska A, Pesce I, Scarduelli G, Potrich C, Lunelli L, Pederzolli C, Pavan P, la Marca G, Pasini L, Ulivi P, Beltran H, Demichelis F, Provenzani A, Quattrone A, D'Agostino VG. (2019). Ultrasensitive detection of cancer biomarkers by nickel-based isolation of polydisperse extracellular vesicles from blood. EBioMedicine. 2019 May;43:114-126. doi: 10.1016/j.ebiom.2019.04.039.

Publications (39):

Human Blood Platelets Adsorption on Polymeric Materials for Liquid Biopsy
Potrich C.; Frascella F.; Bertana V.; Barozzi M.; Vanzetti L.; Piccoli F.; Cristallo A.F.; Malara N.; Pirri C.F.; Pederzolli C.; Lunelli L.
sensors (basel), 22, 2022
DOI: 10.3390/s22134788

Tuning Surface Properties via Plasma Treatments for the Improved Capture of MicroRNA Biomarkers
Speranza, Giorgio; Mele, Gaetano Roberto; Favia, Pietro; Pederzolli, Cecilia; Potrich, Cristina
materials (basel), 15, 2022
DOI: 10.3390/ma15072641

Exploring a new approach for regenerative medicine: Ti-doped polycrystalline diamond layers as bioactive platforms for osteoblast-like cells growth
Carcione R.; Politi S.; Iacob E.; Potrich C.; Lunelli L.; Vanzetti L.E.; Bartali R.; Micheli V.; Pepponi G.; Terranova M.L.; Tamburri E.
applied surface scienceissn: 0169-4332north-holland, 540, 2021
DOI: 10.1016/j.apsusc.2020.148334

Functionalization of TiO2 sol-gel derived films for cell confinement
Pasquardini L.; Roncador A.; Prusakova V.; Vanzetti L.; Potrich C.; Lunelli L.; Pederzolli C.; Iannotta S.; Macchi P.; Dire S.
colloids and surfaces. b, biointerfaces (print), 204, 2021
DOI: 10.1016/j.colsurfb.2021.111787

On-chip purification of tetracyclines based on copper ions interaction
Lunelli L.; Germanis M.; Vanzetti L.; Tatti R.; Potrich C.; Pederzolli C.
sensors (basel), 21, 2021
DOI: 10.3390/s21217236

PDMS-Based Microdevices for the Capture of MicroRNA Biomarkers
Lunelli, Lorenzo; Barbaresco, Federica; Scordo, Giorgio; Potrich, Cristina; Vanzetti, Lia; Marasso, Simone Luigi; Cocuzza, Matteo; Pirri, Candido Fabrizio; Pederzolli, Cecilia
Applied Sciences-basel, 10, 2020
DOI: 10.3390/app10113867

Photofabrication of polymeric biomicrofluidics: New insights into material selection
Fantino, Erika and Chiado, Alessandro and Quaglio, Marzia and Vaghi, Valentina and Cocuzza, Matteo and Marasso, Simone L. and Potrich, Cristina and Lunelli, Lorenzo and Pederzolli, Cecilia and Pirri, Candido F. and Bongiovanni, Roberta and Vitale, Alessandra
materials science & engineering. c, biomimetic materials, sensors and systems (print), 106, 2020
DOI: 10.1016/j.msec.2019.110166

A new silanizing agent tailored to surface bio-functionalization
Lunelli L, Caradonna F, Potrich C, Piotto C, Bettotti P, Vanzetti L, Pederzolli C, Guella G
Colloids and surfaces. B, Biointerfaces, 181, 2019
DOI: 10.1016/j.colsurfb.2019.05.034

AFM1 Detection in Milk by Fab' Functionalized Si3N4 Asymmetric Mach-Zehnder Interferometric Biosensors
Chalyan T, Potrich C, Schreuder E, Falke F, Pasquardini L, Pederzolli C, Heideman R, Pavesi L
Toxins, 11, 2019
DOI: 10.3390/toxins11070409

Prototyping a memristive-based device to analyze neuronal excitability
Lunelli L, Collini C, Jimenez-Garduño AM, Roncador A, Giusti G, Verucchi R, Pasquardini L, Iannotta S, Macchi P, Lorenzelli L, Pederzolli C, Musio C, Potrich C
Biophysical chemistry, 253, 2019
DOI: 10.1016/j.bpc.2019.106212

Simple PDMS microdevice for biomedical applications
Potrich C.; Lunelli L.; Cocuzza M.; Marasso S. L.; Pirri C. F.; Pederzolli C.
talanta (oxf.), 193, 2019
DOI: 10.1016/j.talanta.2018.09.080

3D-printed microfluidics on thin poly(methyl methacrylate) substrates for genetic applications
Bertana V, Potrich C, Scordo G, Scaltrito L, Ferrero S, Lamberti A, Perrucci F, Pirri CF, Pederzolli C, Cocuzza M, Marasso, SL
Journal of Vacuum Science & Technology B, 36, 2018
DOI: 10.1116/1.5003203

Fatigue and biological properties of Ti-6Al-4V ELI cellular structures with variously arranged cubic cells made by selective laser melting
Dallago M, Fontanari V, Torresani E, Leoni M, Pederzolli C, Potrich C, Benedetti M
Journal of mechanical behavior of biomedical materials, 78, 2018
DOI: 10.1016/j.jmbbm.2017.11.044

Innovative silicon microgrippers for biomedical applications: Design, mechanical simulation and evaluation of protein fouling
Potrich C, Lunelli L, Bagolini A, Bellutti P, Pederzolli C, Verotti M, Belfiore NP
Actuators, 7, 2018
DOI: 10.3390/act7020012

miRNA purification with an optimized PDMS microdevice: Toward the direct purification of low abundant circulating biomarkers.
Santini GC, Potrich C, Lunelli L, Vanzetti L, Marasso SL, Cocuzza M, Pirri FC, Pederzolli C
Biophysical chemistry , 229, 2017
DOI: 10.1016/j.bpc.2017.04.009

Primary cortical neurons on PMCS TiO2 films towards bio-hybrid memristive device: A morpho-functional study.
Roncador A, Jimenez-Garduño AM, Pasquardini L, Giusti G, Cornella N, Lunelli L, Potrich C, Bartali R, Aversa L, Verucchi R, Serra MD, Caponi S, Iannotta S, Macchi P, Musio C
Biophysical chemistry , 229, 2017
DOI: 10.1016/j.bpc.2017.04.010

Bio-functional surfaces for the immunocapture of AGO2-bound microRNAs
Vaghi V, Potrich C, Lunelli L, Facci P, Pasquardini L, Vanzetti L, Pederzolli C
Colloids and surfaces. B, Biointerfaces (online), 146, 2016
DOI: 10.1016/j.colsurfb.2016.06.059

On-chip purification and detection of hepatitis C virus RNA from human plasma
Vaghi V.; Potrich C.; Pasquardini L.; Lunelli L.; Vanzetti L.; Ebranati E.; Lai A.; Zehender G.; Mombello D.; Cocuzza M.; Pirri C.F.; Pederzolli C.
Biophysical chemistry, 208, 2016
DOI: 10.1016/j.bpc.2015.06.005

Smart detection of microRNAs through fluorescence enhancement on a photonic crystal
Pasquardini L, Potrich C, Vaghi V, Lunelli L, Frascella F, Descrovi E, Pirri CF, Pederzolli C
Talanta , 150, 2016
DOI: 10.1016/j.talanta.2016.01.002

XPS analysis of genomic DNA adsorbed on PEI-modified surfaces
Vanzetti L, Pasquardini L, Potrich C, Vaghi V, Battista E, Causa F, Pederzolli C
SIA. Surface and interface analysis, 48, 2016
DOI: 10.1002/sia.5932

Enhanced fluorescence detection of miRNA-16 on a photonic crystal
Frascella F.; Ricciardi S.; Pasquardini L.; Potrich C.; Angelini A.; Chiado A.; Pederzolli C.; De Leo N.; Rivolo P.; Pirri C.F.; Descrovi E.
Analyst , 140, 2015
DOI: 10.1039/c5an00889a

Internalization of staphylococcal leukotoxins that bind and divert C5aR is required for intracellular Ca2+ mobilization by human neutrophils.
Tawk, M and Zimmermann-Meisse, G and Bossu, J-L , Potrich, C. , Boucier,T., Dalla Serra, M., Poulain,B. ,Gilles Prévost and Emmanuel Jover
Cellular microbiology , 17, 2015
DOI: 10.1111/cmi.12434

SPAD aptasensor for the detection of circulating protein biomarkers
Pasquardini L.; Pancheri L.; Potrich C.; Ferri A.; Piemonte C.; Lunelli L.; Napione L.; Comunanza V.; Alvaro M.; Vanzetti L.; Bussolino F.; Pederzolli C.
Biosensors & bioelectronics , 68, 2015
DOI: 10.1016/j.bios.2015.01.042

Innovative microRNA purification based on surface properties modulation
Santini G.C.; Potrich C.; Lunelli L.; Pasquardini L.; Vaghi V.; Pederzolli C.
Colloids and surfaces. B, Biointerfaces, 116, 2014
DOI: 10.1016/j.colsurfb.2013.12.033

OncomiR detection in circulating body fluids: A PDMS microdevice perspective
Potrich C.; Vaghi V.; Lunelli L.; Pasquardini L.; Santini G.C.; Ottone C.; Quaglio M.; Cocuzza M.; Pirri C.F.; Ferracin M.; Negrini M.; Tiberio P.; De Sanctis V.; Bertorelli R.; Pederzolli C.
Lab on a chip (online), 14, 2014
DOI: 10.1039/c4lc00630e

p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions
Laventie BJ1, Potrich C, Atmanène C, Saleh M, Joubert O, Viero G, Bachmeyer C, Antonini V, Mancini I, Cianferani-Sanglier S, Keller D, Colin DA, Bourcier T, Anderluh G, van Dorsselaer A, Dalla Serra M, Prévost G
Biochemical journal, 450, 2013
DOI: 10.1042/BJ20121628

The Making of "on-Chip PCR in Real-Time" for Food Quality Control
Potrich C.; Santini G.C.; Lunelli L.; Pasquardini L.; Bertorelli R.; de Sanctis V.; Quattrone A.; Pederzolli C.
BIONANOSCIENCE, 3, 2013
DOI: 10.1007/s12668-013-0080-y

One-shot genetic analysis in monolithic Silicon/Pyrex microdevices
Potrich C; Lunelli L; Pasquardini L; Sonn D; Vozzi D; Dallapiccola R; Marocchi L; Ferrante I; Rossotto O; Pederzolli C
BIOMEDICAL MICRODEVICES, 14, 2012
DOI: 10.1007/s10544-012-9676-1

Organo-silane coated substrates for DNA purification
Pasquardini, L; Lunelli, L; Potrich, C; Marocchi, L; Fiorilli, S; Vozzi, D; Vanzetti, L; Gasparini, P; Anderle, M; Pederzolli, C
APPLIED SURFACE SCIENCE, 257, 2011
DOI: 10.1016/j.apsusc.2011.07.112

Solid phase DNA extraction on PDMS and direct amplification
Pasquardini L, Potrich C, Quaglio M, Lamberti A, Guastella S, Lunelli L, Cocuzza M, Vanzetti L, Pirri CF, Pederzolli C
Lab on a chip, 11, 2011
DOI: 10.1039/c1lc20371a

EPR and FTIR studies reveal the importance of highly ordered sterol-enriched membrane domains for ostreolysin activity.
Rebolj K, Bakrac B, Garvas M, Ota K, Sentjurc M, Potrich C, Coraiola M, Tomazzolli R, Dalla Serra M, Macek P, Sepcic K
Biochimica et biophysica acta. Biomembranes, 1798, 2010

The influence of cholesterol and cone-shaped lipids in Staphylococcus aureus gamma-hemolysins pore formation.
Potrich C, Bastiani H, Colin DA, Huck S, Prevost G, Dalla Serra M
Journal of membrane biology, 227, 2009
DOI: 10.1007/s00232-008-9140-6

Fabrication of a MEMS-based separation module for liquid chromatography.
Benvenuto,A., Guarnieri V., Lorenzelli L., Collini C., Decarli M., Adami A., Potrich C., Lunelli L., Canteri R., and Pederzolli C.
Sensors and actuators. B, Chemical, 130, 2008

Identifying the minimal Cu and Zn binding site sequence in amyloid beta peptides.
Velia Minicozzi;? Francesco Stellato;? Massimiliano Comai;§ Mauro Dalla Serra;§ Cristina Potrich;§1Wolfram Meyer-Klaucke;¶ and Silvia Morante;?2
Journal of biological chemistry, 283, 2008
DOI: 10.1074/jbc.M707109200

Metal binding in amyloid beta-peptides shows intra- and inter-peptide coordination modes
Stellato F., Menestrina G., Dalla Serra M., Potrich C., Tomazzolli R., Meyer-Klaucke W., Morante S.
European biophysics journal, 35, 2006
DOI: 10.1007/s00249-005-0041-7

Structure and activity of the N-terminal region of the eukaryotic cytolysin equinatoxin II.
Drechsler A., Potrich C., Sabo J. K., Frisanco M., Guella G., Dalla Serra M., Anderluh G., Separovic F., Norton R. S.
Biochemistry , 45, 2006
DOI: 10.1021/bi052166o

Cytotoxic activity of a tumor protease-activated pore-forming toxin.
Potrich, C; Tomazzolli, R; DALLA SERRA, Mauro; Anderluh, G; Malovrh, P; Macek, P; Menestrina, G; Mtejuca,
BIOCONJUGATE CHEMISTRY, 16, 2005
DOI: 10.1021/bc049873z

Effects of lipid composition on membrane permeabilization by sticholysin I and II, two cytolysins of the sea anemone Stichodactyla helianthus.
Valcarcel C.A. ; Dalla Serra M. ; Potrich C. ; Bernhart I. ; Tejuca M. ; Martinez D. ; Pazos F. ; Lanio M.E. ; Menestrina G.
BIOPHYSICAL JOURNAL (PRINT), 80, 2001
DOI: 10.1016/S0006-3495(01)76244-

Sizing the radius of the pore formed in erythrocytes and lipid vesicles by the toxin sticholysin I from the sea anemone Stichodactyla helianthus
Tejuca, M; Dalla Serra, M; Potrich, C; Alvarez, C; Menestrina, G
THE JOURNAL OF MEMBRANE BIOLOGY, 183, 2001
DOI: 10.1007/s00232-001-0060-y