Raffaella Barbieri

Research staff

Contact:

- Email raffaella.barbieri@ibf.cnr.it
- Phone +39-010-6475591
- Location Genova

Research interests:

- Migraine and the voltage-gated sodium channel
- Volume-regulated Cl and oxidation-activated K channels in invasiveness and immunotherapy efficiency in human melanoma
- Leveraging basic knowledge of ion channel network in cancer for innovative therapeutic strategies (LIONESS)

Publications (12):

The VRAC blocker DCPIB directly gates the BK channels and increases intracellular Ca2+ in melanoma and pancreatic duct adenocarcinoma cell lines
Zuccolini, Paolo; Ferrera, Loretta; Remigante, Alessia; Picco, Cristiana; Barbieri, Raffaella; Bertelli, Sara; Moran, Oscar; Gavazzo, Paola; Pusch, Michael
british journal of pharmacology, 2022
DOI: 10.1111/bph.15810

Mechanisms of activation of LRRC8 volume regulated anion channels
Bertelli S.; Remigante A.; Zuccolini P.; Barbieri R.; Ferrera L.; Picco C.; Gavazzo P.; Pusch M.
cellular physiology and biochemistryissn: 1015-8987s. karger, 55, 2021
DOI: 10.33594/000000329

Gain of function of sporadic/familial hemiplegic migraine-causing SCN1A mutations: Use of an optimized cDNA
Bertelli S, Barbieri R, Pusch M, Gavazzo P
Cephalalgia, 39, 2019
DOI: 10.1177/0333102418788336

Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene
Barbieri R.; Bertelli S.; Pusch M.; Gavazzo P.
the journal of headache and pain (testo stamp.), 20, 2019
DOI: 10.1186/s10194-019-1056-2

Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice
Barbieri, R. and Contestabile, A. and Ciardo, M.G. and Forte, N. and Marte, A. and Baldelli, P. and Benfenati, F. and Onofri, F.
oncotarget, 9, 2018
DOI: 10.18632/oncotarget.24655

Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression
Baroni, Debora; Picco, Cristiana; Barbieri, Raffaella; Moran, Oscar
Biology of the cell, 106, 2014
DOI: 10.1111/boc.201300040

Identification of an intra-molecular disulfide bond in the sodium channel beta 1-subunit
Barbieri R; Baroni D; Moran O
Biochemical and biophysical research communications, 420, 2012

Regulation of innate immunity by the nucleotide pathway in children with idiopathic nephrotic syndrome
Bertelli R, Bodria M, Nobile M, Alloisio S, Barbieri R, Montobbio G, Patrone P, Ghiggeri GM
Clinical and experimental immunology, 166, 2011

Evidence for two conductive pathways in P2X(7) receptor: differences in modulation and selectivity.
Alloisio S, Di Garbo A, Barbieri R, Bozzo L, Ferroni S, Nobile M
Journal of neurochemistry, 113, 2010

Evidence for two conductive pathways in P2X7 receptor: differences in modulation and selectivity.
Alloisio, S; Di Garbo, A; Barbieri, R; Bozzo, L; Ferroni, S; Nobile, M
JOURNAL OF NEUROCHEMISTRY, 113, 2010
DOI: 10.1111/j.1471-4159.2010.06649.x

Differential crosstalk between P2X7 and arachidonic acid in activation of mitogen-activated protein kinases
Barbieri R.*; Alloisio S.*; Ferroni S.°; Nobile M.*
Neurochemistry international, 53, 2008
DOI: 10.1016/j.neuint.2008.05.001

Functional evidence for presynaptic P2X7 receptors in adult rat cerebrocortical nerve terminals
Susanna Alloisio(a); Chiara Cervetto(b); Mario Passalacqua(c); Raffaella Barbieri(a); Guido Maura(b,d,e); Mario Nobile(a); Manuela Marcoli(b)
FEBS letters, 582, 2008
DOI: 10.1016/j.febslet.2008.10.041