Liposome as drug delivery system

Liposomes are lipid nanoparticles, potentially biocompatible and blood brain barrier crossing. Due to their structural properties they can load hydrophylic and hydrophobic molecules. Different lipid composition or addition of tails lead to different physico-chemical properties and likely to different ways to interact with the in vivo system. A biophysical characterization of potential drug delivery matrices and the interaction study with serum components, such as serum proteins, is an useful strategy to better understand how to improve in vivo life time of the nanoparticles.

Members:
Rita Carrotta (Principal investigator)
Maria Assunta Costa
Fabio Librizzi
Maria Rosalia Mangione